- Genus Acinonyx Brookes, 1828
- Genus Caracal Gray, 1843
- Genus Catopuma Severtzov, 1858
- Genus Felis Linnaeus, 1758
- Genus Herpailurus Severtzov, 1858
- Genus Leopardus Gray, 1842
- Leopardus braccatus Cope, 1889 – pantanal cat
- Leopardus colocolo Molina, 1782 – colocolo
- Leopardus geoffroyi d'Orbigny & Gervais, 1844 – Geoffroy's cat
- Leopardus guigna Molina, 1782 – kodkod
- Leopardus guttulus Hensel, 1872 – southern tiger cat
- Leopardus jacobitus Cornalia, 1865 – Andean mountain cat
- Leopardus pajeros Desmarest, 1816 – pampas cat
- Leopardus pardalis Linnaeus, 1758 – ocelot
- Leopardus tigrinus Schreber, 1775 – oncilla
- Leopardus wiedii Schinz, 1821 – margay
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